A “Plain-Jane” designer is having difficultly standing out in the world of high fashion among flawlessly beautiful models including her own roommate. Relegated to the role of seamstress for a world-renowned designer, Sarah wants nothing more than to be noticed for her own designs. When she witnesses the closeness of her model roommate with Brad, the photographer she has grown close to, Sarah rushes from a party feeling angry and hurt. A resulting traffic accident leaves her with significant scars on her face and body.
Based on the referral from her apologetic roommate, Sarah meets with a renowned plastic surgeon that convinces her to undergo a highly experimental healing procedure that uses stems cells to speed up and improve healing. She recovers to find herself looking as beautiful as the models she works with. Sarah finds her confidence and sexual appetite is also increased leading to several torrid sexual encounters.
Unbeknownst to her, Sarah sets off a spiraling contagion, as within 24 hours her lovers become rabid, violent spreaders of death and disease. As the disease mutates, it spreads through society at an accelerated rate causing an ever-increasing number of people to rampage through the streets in a violent and bloody killing spree.
The now out of control disease draws the attention of the CDC and the nefarious plastic surgeon out to find the cure. The spreading violence around them impedes them from discovering the truth. Sarah is both the source of the disease and its cure…and time is running out.